PRACTICAL BIOINFORMATICIAN, THE IBD

Sinopse

áComputer scientists have increasingly been enlisted as &ldquo,bioinformaticians&rdquo, to assist molecular biologists in their research. This book is a practical introduction to bioinformatics for these computer scientists. The chapters are in-depth discussions by expert bioinformaticians on both general techniques and specific approaches to a range of selected bioinformatics problems. The book is organized into clusters of chapters on the following topics:&bull, Overview of modern molecular biology and a broad spectrum of techniques from computer science &mdash, data mining, machine learning, mathematical modeling, sequence alignment, data integration, workflow development, etc.&bull, In-depth discussion of computational recognition of functional and regulatory sites in DNA sequences.&bull, Incisive discussion of computational prediction of secondary structure of RNA sequences.&bull, Overview of computational prediction of protein cellular localization, and selected discussions of inference of protein function.&bull, Overview of methods for discovering protein&ndash,protein interactions.&bull, Detailed discussion of approaches to gene expression analysis for the diagnosis of diseases, the treatment of diseases, and the understanding of gene functions.&bull, Case studies on analysis of phylogenies, functional annotation of proteins, construction of purpose-built integrated biological databases, and development of workflows underlying the large-scale-effort gene discovery.